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Finasteride Hair Loss Medicine Raw Material 98319-26-7 White Powder For

Finasteride Hair Loss Medicine Raw Material 98319-26-7 White Powder For

Brand Name : PooChun
Model Number : CAS 98319-26-7
Certification : ISO9001 SGS HACCP
Place of Origin : China
MOQ : Negotiable
Price : Negotiable
Payment Terms : T/T, L/C, Western Union, MoneyGram
Supply Ability : 100 ton per Month
Delivery Time : 1-3days after payment
Packaging Details : 1~10 kg / Al-Pt bag,10kg / 25kg fiber drum
CAS : 98319-26-7
Appearance : White powder
Other name : Finastid; Propecia; Finpecia; N - tert - Butyl - 3 - oxo - 4- aza - 5α - androst - 1- en -17β - carboxamide; Finasteride; Proscar; MK 906
Payment terms : T/T, Western Union, Paypal, Moneygram
Trade terms : FOB CNF CIF DAP DDU
Shipping : DHL TNT FedEx HKEMS UPS
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Finasteride Medicine Raw Material For prostatic hyperplasia male pattern hair loss 98319-26-7



Description


Finasteride is a 4 - azotypic compound, which is a specific inhibitor of intracellular enzyme - II type 5a - reductase in the process of testosterone metabolism. Benign prostatic hyperplasia or prostatic hypertrophy depends on the conversion of testosterone into dihydrotestosterone in the prostate.


This drug can effectively reduce blood and dihydrotestosterone in the prostate gland. The androgen receptor has no affinity for the androgen receptor. Finasteride belong to 5 alpha reductase inhibitors, the mechanism is through its hormone, the inhibition of testosterone into dihydrotestosterone (DHT), increase the shrinkage and improve symptoms of prostate and urinary flow rate, prevention of benign prostatic hyperplasia ( BPH ).


Function


This medication in a long - term efficacy and safety of ( PLESS ), in the study of symptoms of moderate to severe hyperplasia of prostate, 3016 prostate hyperplasia patients treated with this drug is 4 years relevant disposal ( surgical intervention ), urinary system such as transurethral resection of the prostate gland and other resection of the prostate, or need to insert the catheter acute urinary retention is evaluated.In this double - blind, randomized, placebo - controlled, multicenter study, treatment with this drug to the disposal of the overall risk of urinary system was reduced by 51%, with significant and sustained of prostate volume shrinking, and continuous maximum urinary flow rate increased and the symptoms improve.


Pharmacological effects


Finasteride is 4 - nitrogen compounds of steroid hormones, for specific Ⅱ type 5 alpha reductase inhibitors, inhibition of peripheral testosterone into dihydrotestosterone ( DHT ), reduce blood and prostate, skin, etc in DHT levels in the organization.The growth and development of the prostate and benign hyperplasia depends on DHT, finasteride by lowering blood and DHT levels in the prostate tissue and suppress hyperplasia of prostate and improve the related clinical symptoms of benign prostatic hyperplasia.


Indications


Used to treat prostatic hyperplasia.


Applicable people


BPH patients with enlarged prostate and lower urinary tract symptoms.

Patients with higher prostate volume ( 40ml ) and / or serum PSA levels ( PSA than 1.4ng/ml ) had better results


Specification


Test ItemsSpecificationTest Results
DescriptionWhite or off-white crystalline powderOff-white crystalline powder
Specific rotation-56°~-60°-58.2°
IdentificationIRMatches with working standardComplies
HPLC
SolubilityFreely soluble in chloroform and in alcohol;
Very slightly soluble in water
Conform
Heavy metals≤10ppm<10ppm
Water≤0.3%0.22%
Residue on ignition≤0.1%0.05%
Relative materialMaximum impurities≤0.5%0.36%
Total impurities≤1.0%0.52%
Assay98.5~101.0%99.59%
ConclusionThe specification conform with Enterprise standard


Product Tags:

pharmaceutical intermediates

      

pharmaceutical raw materials

      
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Finasteride Hair Loss Medicine Raw Material 98319-26-7 White Powder For Images

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