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Low Toxicity P Acetophenetidide / Phenacetin 62-44-2 For Fever Headache

Low Toxicity P Acetophenetidide / Phenacetin 62-44-2 For Fever Headache

Brand Name : PooChun
Model Number : CAS 62-44-2
Certification : ISO9001 SGS HACCP
Place of Origin : China
MOQ : Negotiable
Price : Negotiable
Payment Terms : T/T, L/C, Western Union, MoneyGram
Supply Ability : 100 ton per Month
Delivery Time : 1-3days after payment
Packaging Details : 1~10 kg / Al-Pt bag,10kg / 25kg fiber drum
CAS : 62-44-2
Appearance : White powder
Other name : p-Acetophenetidide; Acetamide, N-(4-ethoxyphenyl)-; Achrocidin; p-ethoxyacetanilide; Codempiral
Payment terms : T/T, Western Union, Paypal, Moneygram
Trade terms : FOB CNF CIF DAP DDU
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Low Toxicity P Acetophenetidide / Phenacetin 62-44-2 For Fever Headache Neuropathic Pain



Description


Phenacetin ( or acetophenetidin ) is a pain-relieving and fever - reducing drug, which was widely used between its introduction in 1887 and the 1983 ban imposed by the U.S. Food and Drug Administration.


Antipyretic analgesic, used to treat fever headache, neuropathic pain, etc. The effect of relieving heat is stronger than analgesic effect.The intensity of the drug is comparable to that of aspirin, which is slow and persistent and has low toxicity.The study showed that this product and its metabolite paracetamol have a pyrolytic effect.Because of the enzyme inhibitors, it can still show a clear thermal effect when it is not converted to acetaminophen.


Therefore, the pyrolytic effects of the products are not only produced by their active product paracetamol.The mild analgesic effect of phenacidine usually lasts 3-4 hours.The synergistic effect of the salicylic acid is enhanced.It is mainly used in the antipyretic analgesia of small animals.This product is also one of the components of APC tablets.


Pharmacokinetic


This article mainly in the liver metabolism for acetaminophen, a small number of the deacelation and phenetidine in pairs, after further metabolized to the amino quinone can make hemoglobin oxidized to methemoglobin, can appear when large amount of purple purple, even severe hypoxia symptoms, especially in children.


Indications


This product is mainly used to relieve heat and pain and has been replaced by acetaminophen, which is only used in some compound preparations.


Contraindication


1. Disable the allergy of this product, pregnant woman and lactation;

2. Disables of liver and kidney function;

3. Patients with hemolytic disease or other blood disease history are disabled;

4. Old people and children should be careful.


Specification


Product name


Phenacetin


CAS No.

62-44-2


Outer Packing

25KG


Production date

2016.05.07


Shelf life
2019.05.05


Standard adopted


BP68


Items of analysis


Specification


Results


Description


Should comply with the standard


Comforms


Identification


Positive


Positive


Melting point


134ºC to 136.5ºC


134.5ºC to 136.5ºC


4-chloroacetanilide


BP1968


<3.5ml/0.6g


P-Phenetidine


BP1968


Comforms


Sulphated ash


≤0.1%


0.07%


Assay


≥99%


99.1%

80
through a uss#80



98%


Conclusion


Qualified



Product Tags:

steroid hormones

      

pharmaceutical raw materials

      
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